Organic Pau D'arco Morado (Purple) | Lapacho Brazil

Lapacho is the name of the tree. Its dried bark is used for tea. Originated in South America and the Andes.
		Effect The active ingredients in Lapacho are lapachol and beta-apache, antibiotic agents that are found suitable in the treatment of a number of diseases: rheumatism, atherosclerosis, asthma, bronchitis, inflammation of the colon, bladder, and prostate, varicose veins, skin diseases, hard-to-heal wounds, anemia, a weakened immune system and lymphatic system, liver insufficiency, cancer, diabetes, metabolic disruption, viral diseases, and gastric ulcers. We use lapacho morado to treat yeast syndrome and the gut.  It is credited with improving digestion. It has medical uses, such as the control of parasites. It cleanses the body of toxins and stimulates the digestive tract, especially the intestines, liver, gall bladder, and sweat glands. It is attributed to being analgesic, sedative, hypotensive, and diuretic. Lapacho brew is regarded as a rich source of iron, calcium, potassium, magnesium, and copper. Side effects and indications: It is not recommended to use Lapacho in cases of pregnancy or lactation.

The following is a list of some of the effects of lapacho and/or any of its components that modern research has supported:

1. Laxative effect. Regular use of lapacho will maintain the regularity of bowel movements. This property is undoubtedly due to the presence of napthaquinones and anthraquinones. Users of lapacho universally report a pleasant and moderate loosening of the bowels that leads to greater regularity without any unpleasant side-effects such as diarrhea.

2. anti-cancer effect. The greater part of the basic research on lapacho, both in the United States and in other countries, has dealt directly with the cancer question.

3. Anti-oxidant effect. In vitro trials show definite inhibition of free radicals and inflammatory leukotrienes by lapacho constituents. This property might underlie the effectiveness of lapacho against skin cancer and definitely helps to explain observed anti-aging effects. Modern science has recently uncovered the importance of free radicals in the generation of many debilitating diseases, from cancer to arthritis. These molecules are even more heavily implicated in the normal aging process. Reversing their action has become big business in world health circles. Anti-oxidants, or free-radical scavengers, have emerged as premier candidates for the roles of healers and disease-preventers. Among the antioxidants, few have greater potency than lapacho and other constituents of lapacho.

4. Analgesic effect. The administration of lapacho is consistently credited in reports issuing from South American clinics as a primary modality for lessening the pain associated with several kinds of cancer, especially cancer of the prostate, liver, or breast. Arthritic pain has also been relieved with lapacho ingestion.

5. Antimicrobial/anti-parisiticidal effects. includes inhibition and destruction of gram-positive and acid-fast bacteria (B. subtilis, M. pyogenes aureus, etc.), yeasts, fungi, viruses, and several kinds of parasites. Two troublesome families of viruses inhibited by lapachol are noteworthy: herpes viruses and HIV's. Together, these viruses account for much of mankind's misery. The anti-malaria activity of lapacho spawned a great deal of research interest in the early decades of this century. A 1948 article reviewed the progress and indicated that the N-factors, especially lapachol, were among the most promising anti-malarial substances known at that time. Lapacho's immunostimulating action is due in part to its rather potent antimicrobial effects.

6. anti-fungal effect. Lapacho is often singled out as the premier treatment for Candida or yeast infections. Lapachol, N-factors, and xyloidone appear to be the primary active principles.9/10 By the mid-70s, the list of N-factors that inhibited Candida albicans and other fungi had grown to several dozen.11-15

It would be misleading to categorically state that the N-factors in lapacho have proven antimicrobial and anti-fungal activity in and of themselves. Studies have shown that the manner in which they occur in the plant must be taken into consideration. We know, for example, that anti-fungal activity is lost when the N-factors are tightly bound to highly water-soluble or highly fat-soluble groups. It has not been clearly determined how the N-factors occur in lapacho.16

N-factors, obtainable from various chemical supply companies, have become favorite testing agents in government and university labs due to the rise in yeast infections resulting from increased use of cytotoxic drugs, corticosteroids, antibiotics, and immunosuppressants.17-18

An interesting application has been reported in which toe and fingernail fungi infections are relieved by soaking these appendages in lapacho tea off and on for a couple of weeks.

7. Anti-inflammatory. The anti-inflammatory and healing action of lapacho extracts was demonstrated in a study in which purple lapacho extract was administered to patients with cervicitis and cervical vaginitis, conditions resulting variously from infections (Candida albicans, Trichomonas vaginalis) and chemical irritations. 

ANTI-VIRAL

One of the strongest actions of lapacho is against viruses. The range of viruses inactivated by lapacho extends from those that cause the common cold to those that are responsible for AIDS. It has been shown to actively inhibit, kill, or stunt the growth of several dangerous viruses, including herpes virus Hominis types I and II, polio virus, vesicular stomatitis virus, avian myeloblastosis virus, rauscho murine leukemia virus, friend virus, and rous sarcoma virus. 20-24 The N- and A-factors in lapacho also inhibit several other viruses.

One N-factor, beta-lapachone, inhibits enzymes in virus cells that directly affect the synthesis of DNA and RNA. It is also a potent inhibitor of the enzyme reverse transcriptase, involved in RNA-DNA relationships. Once these processes are inhibited, the virus is unable to take over the reproductive processes of the cell and cannot, therefore, replicate itself and infect other cells. Such inhibition is a characteristic of most substances that are being tested for activity against AIDS and Epstein-Barr. The enzyme in question is a key to the action of retroviruses. These viruses, also known as ribodeoxyviruses or oncornaviruses, have been implicated in the development of several kinds of experimental cancers. Beta-lapachone is obtained simply by treating lapachol with sulfuric acid, and tests show that it has a unique method of action vis-à-vis reverse transcpritase inhibition.25

CELLULAR MECHANICS

Every cell of the body requires oxygen and glucose to obtain energy for life-

sustaining functions. Oxygen and glucose are subjected to a fairly complex

metabolic process in the tiny energy-producing structures in the cell called

mitochondria. This process requires numerous enzymes and coenzymes. The

oxygen and glucose are converted to carbon dioxide and water, which are then

returned to the blood. CO2 is exhaled by the lungs (hence this metabolic process).

is often called "respiration"); excess water is eventually drawn off through

perspiration or through the kidneys. During this conversion, several free electrons

are freed up, which are immediately utilized by another pathway to produce ATP

(adenosine triphosphate), the energy currency of the cell--ATP is the molecule every

cell is required to utilize, or spend, to obtain energy. The two paths--one for

breakdown of glucose, and one for the synthesis of ATP—are tightly coupled together.

Should they become uncoupled, the cell can no longer obtain energy, and it dies. 

Such poisoning has acquired the name of "uncoupling of oxidative

phosphorylation."

Many agents have been found to uncouple oxidative phosphorylation; many of them resemble the N-factors in lapacho. In fact, it has been found that lapacho works like other benzoquionones, i.e., it uncouples the mitochondrial oxidative phosphorylation occurring in cancerous cells but not in healthy ones.35 This selective killing (cytotoxicity) of tumor cells is what makes lapacho such a potentially valuable agent for the treatment of cancer.

One of the games science plays is attempting to discover at what point cellular respiration is broken up by chemical agents The components of lapacho seem to interrupt the process at several points, usually by inhibiting an enzyme or coenzyme that is required for the next step in the chain to occur properly.36-38 For instance, lapacho inhibits the proper functioning of ATPase, the enzyme that catalyzes the final step in the formation of ATP.39

Lapachol has also been shown to inhibit the amount of another substance required for cellular reproduction: uridine triphosphate.40 This molecule is the main source of substances (called pyrimidine nucleotides) that are required by cells in order to build DNA, RNA, and most other important proteins in the body. Lapacho may actually block the syntheses of pyrimidines in cancer cells by inhibiting the enzyme dihydroorotate dehydrogenase).41 The result would be certain cellular death.

There is also evidence that lapachol interacts directly with the nucleic acids of the DNA helix in cancerous cells.42 If such interaction, or bonding, takes place, then DNA replication would be impossible. The result is also the eventual death of the cell.

Lastly, beta-lapachone, a component of lapacho, has been shown to weaken cancer cells until they die. It does this by speeding up a process called lipid peroxidation, which makes harmful molecules. 43

The clinical study was done in Brazil. read more https://mujerdeconocimiento.com/blogs/pau-darco